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This book focuses on the environmental impact of pollution and the role of wetlands in water treatment. It provides current information on the construction, performance, operation, and maintenance of subsurface flow constructed wetlands for domestic and municipal wastewater. The study evaluates the treatment performance of horizontal subsurface flow wetlands for domestic wastewater, aiming to establish safe discharge limits for agricultural drains. It includes modeling and statistical analyses of treated water samples and the design of artificial neural network models to simulate experimental data.